Dr Siouxsie Wiles has made a career of combining her twin passions of bioluminescence (think glow worms and fireflies) and infectious diseases. Siouxsie studied medical microbiology at the University of Edinburgh, UK and did a PhD in microbiology at the Centre for Ecology and Hydrology in Oxford. She spent her postdoctoral years at Imperial College London where her work culminated in winning the inaugural UK National Centre for the Replacement, Refinement and Reduction of Animals in Research prize. In 2009, Siouxsie was awarded a Sir Charles Hercus Fellowship from the Health Research Council of New Zealand and relocated to the University of Auckland where she now heads up the Bioluminescent Superbugs Lab. Siouxsie has a keen interest in demystifying science for the public; she is a tweeter, blogger, podcaster and radio science commentator. She also works with graphic artists and illustrators to make animations about bioluminescence and science, and to produce public art exhibits using harmless naturally glowing bacteria. Siouxsie has won the trifecta of New Zealand science communication prizes for her efforts, starting with New Zealand Association of Scientists (NZAS) Science Communicator award in 2012 and followed by the Prime Minister’s Science Media Prize and Royal Society of New Zealand Callaghan Medal in 2013.